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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2A All Species: 63.94
Human Site: Y63 Identified Species: 87.92
UniProt: P49459 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49459 NP_003327.2 152 17315 Y63 T I E F T E E Y P N K P P T V
Chimpanzee Pan troglodytes XP_001137388 247 26879 Y158 T I E F T E E Y P N K P P T V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_549217 224 24534 Y135 T I E F T E E Y P N K P P T V
Cat Felis silvestris
Mouse Mus musculus Q9Z255 152 17297 Y63 T I E F T E E Y P N K P P T V
Rat Rattus norvegicus P63149 152 17294 Y63 V I E F S E E Y P N K P P T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512900 156 17521 Y67 V I E F S E E Y P N K P P T V
Chicken Gallus gallus
Frog Xenopus laevis P56616 179 19879 Y89 S L E F P S G Y P Y N A P T V
Zebra Danio Brachydanio rerio NP_956013 152 17267 Y63 T V E F T E E Y P N K P P T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25153 151 17134 Y63 T I E F T E E Y P N K P P T V
Honey Bee Apis mellifera XP_624240 151 17198 Y63 T I E F T E E Y P N K P P T V
Nematode Worm Caenorhab. elegans P52478 192 21494 Y63 S L E F T E E Y P N K P P T V
Sea Urchin Strong. purpuratus XP_795976 139 15590 K51 F T E E Y P N K P P T V R F V
Poplar Tree Populus trichocarpa XP_002319717 152 17330 Y63 T L Q F T E D Y P N K P P T V
Maize Zea mays NP_001146868 152 17321 Y63 T L Q F T E D Y P N K P P T V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P25865 152 17263 Y63 S L Q F S E D Y P N K P P T V
Baker's Yeast Sacchar. cerevisiae P06104 172 19687 Y63 L L E F D E E Y P N K P P H V
Red Bread Mold Neurospora crassa P52493 151 17245 Y63 V M H F E E Q Y P N K P P S V
Conservation
Percent
Protein Identity: 100 61.5 N.A. 67.8 N.A. 100 95.3 N.A. 85.9 N.A. 39.1 98.6 N.A. 87.5 87.5 67.7 82.8
Protein Similarity: 100 61.5 N.A. 67.8 N.A. 100 96.7 N.A. 88.4 N.A. 54.7 99.3 N.A. 93.4 93.4 75.5 86.1
P-Site Identity: 100 100 N.A. 100 N.A. 100 86.6 N.A. 86.6 N.A. 46.6 93.3 N.A. 100 100 86.6 20
P-Site Similarity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 93.3 N.A. 60 100 N.A. 100 100 100 20
Percent
Protein Identity: 77.6 76.9 N.A. 75.6 61 67.7
Protein Similarity: 92.1 92.1 N.A. 92.1 75 83.5
P-Site Identity: 80 80 N.A. 66.6 73.3 60
P-Site Similarity: 100 100 N.A. 100 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 6 0 18 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 77 6 6 89 65 0 0 0 0 0 0 0 0 % E
% Phe: 6 0 0 95 0 0 0 0 0 0 0 0 0 6 0 % F
% Gly: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % G
% His: 0 0 6 0 0 0 0 0 0 0 0 0 0 6 0 % H
% Ile: 0 48 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 6 0 0 89 0 0 0 0 % K
% Leu: 6 36 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 6 0 0 89 6 0 0 0 0 % N
% Pro: 0 0 0 0 6 6 0 0 100 6 0 89 95 0 0 % P
% Gln: 0 0 18 0 0 0 6 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % R
% Ser: 18 0 0 0 18 6 0 0 0 0 0 0 0 6 0 % S
% Thr: 53 6 0 0 59 0 0 0 0 0 6 0 0 83 0 % T
% Val: 18 6 0 0 0 0 0 0 0 0 0 6 0 0 100 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 95 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _